2017

Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma.
Po A, Silvano M, Miele E, Capalbo C, Eramo A, Salvati V, Todaro M, Besharat ZM, Catanzaro G, Cucchi D, Coni S, Di Marcotullio L, Canettieri G, Vacca A, Stassi G, De Smaele E, Tartaglia M, Screpanti I, De Maria R, Ferretti E.
Oncogene. 2017 Apr 3. doi: 10.1038/onc.2017.91

2014

Conti F, Spinelli FR, Alessandri C, Pacelli M, Ceccarelli F, Marocchi E, Montali A, Capozzi A, Buttari B, Profumo E, Sorice M, Arca M, Valesini G, Riganò R. Subclinical Atherosclerosis in Systemic Lupus Erythematosus and Antiphospholipid Syndrome: Focus on β2GPI-Specific T Cell Response. Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):661-8.

2013

Valle A, Giamporcaro GM, Scavini M, Stabilini A, Grogan P, Bianconi E, Sebastiani G, Masini M, Maugeri N, Porretti L, Bonfanti R, Meschi F, De Pellegrin M, Lesma A, Rossini S, Piemonti L, Marchetti P, Dotta F, Bosi E, Battaglia M. Reduced circulating neutrophils precedes and accompanies type 1 diabetes. Diabetes. (2013) PMID: 23349491.

Durante C, Montesano T, Torlontano M, Attard M, Monzani F, Tumino S, Costante G, Meringolo D, Bruno R, Trulli F, Massa M, Maniglia A, D’Apollo R, Giacomelli L, Ronga G, Filetti S; PTC Study Group. Papillary thyroid cancer: time course of recurrences during postsurgery surveillance. J Clin Endocrinol Metab. 2013 Feb;98(2):636-42.

Durante C, Costante G, Filetti S. Differentiated thyroid carcinoma: defining new paradigms for the post-operative management. Endocr Relat Cancer. 2013 Apr 9. PubMed PMID: 23572163.

Russo D, Durante C, Bulotta S, Puppin C, Puxeddu E, Filetti S, Damante G. Targeting histone deacetylase in thyroid cancer. Expert Opin Ther Targets. 2013 Feb;17(2):179-93.

Spagnuolo I, Patti A, Sebastiani G, Cataldo D, Dotta F. The case for virus-induced T1D. Curr Opin Endocrinol Diabetes. (2013)  In press

Sebastiani G, Nigi L, Spagnuolo I, Morganti E, Fondelli C, Dotta F. MicroRNA profiling in sera of patients with type 2 diabetes mellitus reveals an upregulation of miR-31 expression in subjects with microvascular complications. Journal of Biomedical Science and Engineering (JBiSE). (2013) In press

Maggisano V, Puppin C, Celano M, D’Agostino M, Sponziello M, Micali S, Navarra M, Damante G, Filetti S, Russo D. Cooperation of histone deacetylase inhibitors SAHA and valproic acid in promoting sodium/iodide symporter expression and function in rat Leydig testicular carcinoma cells. Endocrine. 2013 May 1. PubMed PMID: 23636804.

Durante C, Paciaroni A, Plasmati K, Trulli F, Filetti S. Vandetanib: opening a new treatment practice in advanced medullary thyroid carcinoma. Endocrine. 2013 Apr 14. PubMed PMID: 23584948.

Celano M, Sponziello M, Tallini G, Maggisano V, Bruno R, Dima M, Di Oto E, Redler A, Durante C, Sacco R, Filetti S, Russo D. Increased expression of pro-angiogenic factors and vascularization in thyroid hyperfunctioning adenomas with and without TSH receptor activating mutations. Endocrine. 2013 Feb;43(1):147-53.

Tortosa F, Dotta F. Incretin Hormones and Beta-cell mass expansion: what we know and what is missing? Arch Physiol Biochem. (2013) PMID: 23697580.

Ceccarelli E, Gennari L, Guarino E, Merlotti D, Patti A, Nuti R, Dotta F. Beyond glycemic control in diabetes mellitus: effects of incretin-based therapy on bone metabolism. Front Endocrinol. (2013)  In press

2012

Coppieters KT, Dotta F, Amirian N, Campbell PD, Kay TW, Atkinson MA, Roep BO, von Herrath MG. Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. J Exp Med. (2012); 209(1): 51-60.

Takiishi T, Korf H, Van Belle TL, Robert S, Grieco FA, Caluwaerts S, Galleri L, Spagnuolo I, Steidler L, Van Huynegem K, Demetter P, Wasserfall C, Atkinson MA, Dotta F, Rottiers P, Gysemans C, Mathieu C. Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice. J Clin Invest. (2012); 122(5): 1717-1725.

Marchetti P, Lupi R, Bugliani M, Kirkpatrick CL, Sebastiani G, Grieco FA, Del Guerra S, D’Aleo V, Piro S, Marselli L, Boggi U, Filipponi F, Tinti L, Salvini L, Wollheim CB, Purrello F, Dotta F. A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets. Diabetologia; (2012) 55(12): 3262-3272.

Gennari L, Merlotti D, Valenti R, Ceccarelli E, Ruvio M, Pietrini MG, Capodarca C, Franci MB, Campagna MS, Calabrò A, Cataldo D, Stolakis K, Dotta F, Nuti R. (2012) Circulating sclerostin levels and bone turnover in type 1 and type 2 diabetes. J Clin Endocrinol Metab.; 97(5): 1737-1744.

Durante C, Montesano T, Attard M, Torlontano M, Monzani F, Costante G, Meringolo D, Ferdeghini M, Tumino S, Lamartina L, Paciaroni A, Massa M, Giacomelli L, Ronga G, Filetti S; PTC Study Group. Long-term surveillance of papillary thyroid cancer patients who do not undergo postoperative radioiodine remnant ablation: is there a role for serum thyroglobulin measurement? J Clin Endocrinol Metab. 2012 Aug;97(8):2748-53.

Passon N, Puppin C, Lavarone E, Bregant E, Franzoni A, Hershman JM, Fenton MS, D’Agostino M, Durante C, Russo D, Filetti S, Damante G. Cyclic AMP-response element modulator inhibits the promoter activity of the sodium iodide symporter gene in thyroid cancer cells. Thyroid. 2012 May;22(5):487-93.

D’Agostino M, Voce P, Celano M, Sponziello M, Moretti S, Maggisano V, Verrienti A, Durante C, Filetti S, Puxeddu E, Russo D. Sunitinib exerts only limited effects on the proliferation and differentiation of anaplastic thyroid cancer cells. Thyroid. 2012 Feb;22(2):138-44.

Maranghi M, Prudente S, D’Erasmo L, Morini E, Ciociola E, Coletta P, Verrienti A, Arciello S, Copetti M, Pellegrini F, Santini SA, Morano S, Filetti S, Trischitta V. The ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) K121Q polymorphism modulates the beneficial effect of weight loss on fasting glucose in non-diabetic individuals. Nutr Metab Cardiovasc Dis. 2012 Mar 6. 

Zorzi F, Zuzzi S, Onali S, Calabrese E, Condino G, Petruzziello C, Ascolani M, Pallone F, Biancone L. Efficacy and safety of infliximab and adalimumab in Crohn’s disease: a single centre study. Aliment Pharmacol Ther. 2012 Jun;35(12):1397-407.

Grieco FA, Sebastiani G, Spagnuolo I, Patti A, Dotta F. Immunology in the clinic review series; focus on type 1 diabetes and viruses: how viral infections modulate beta cell function. Clin Exp Immunol. (2012); 168(1): 24-29. 3.360

F. Conti, C. Alessandri, M. Sorice, A. Capozzi, A. Longo, T. Garofalo, R. Misasi, D. Bompane, G. R. V. Hughes, M. A. Khamashta, G. Valesini. Thin-layer chromatography immunostaining in detecting anti-phospholipid antibodies in seronegative anti-phospholipid syndrome. Clin Exp Immunol. 167:429-437; 2012.

Guarino E, Nigi L, Patti A, Fondelli C, Dotta F. Combination therapy with metformin plus vildagliptin in type 2 diabetes mellitus. Expert Opin Pharmacother. (2012); 13(9): 1377-84.

Gallo R, Natale M, Vendrame F, Boggi U, Filipponi F, Marchetti P, Laghi Pasini F, Dotta F. In vitro effects of mycophenolic acid on survival, function, and gene expression of pancreatic beta-cells. Acta Diabetol. (2012) Jan 17. PMID: 22249339.

Calabrese E, Zorzi F, Zuzzi S, Ooka S, Onali S, Petruzziello C, Lasinio GJ, Biancone L, Rossi C, Pallone F. Development of a numerical index quantitating small bowel damage as detected by ultrasonography in Crohn’s disease. J Crohns Colitis. 2012 Feb 23. 

Vendrame F, Cataldo D, Ciarlo L, Umland O, Misasi R, Dotta F. In type 1 diabetes immunocompetent cells are defective in IL-16 secretion. Scand J Immunol. (2012); 75(1): 127-128.

Coletta P, Barbarossa G, Pergolini D, D’Erasmo L, Renzi A, Mercuri L, Anatra MG, Ciociola E, Verrienti A, Maranghi M. Genetic determinants and early carotid atherosclerosis: is there a role for the ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP-1) K121Q polymorphism? Preliminary results in non diabetic individuals. 2012 Endocrine.Dec;42(3):749-51.

Galleri L, Sebastiani G, Vendrame F, Grieco FA, Spagnuolo I, Dotta F. Viral Infections and Diabetes. Adv Exp Med Biol; (2012) 771: 252-271.

S. Colafrancesco, R. Priori, C.Alessandri, C. Perricone, M. Pendolino, G. Picarelli, and G. Valesini IL-18 Serum Level in Adult Onset Still’s Disease: A Marker of Disease Activity. International Journal of Inflammation Volume 2012, Article ID 156890, 6 pages doi:10.1155/2012/156890

2011

Stolfi C, Rizzo A, Franzè E, Rotondi A, Fantini MC, Sarra M, Caruso R, Monteleone I, Sileri P, Franceschilli L, Caprioli F, Ferrero S, MacDonald TT, Pallone F, Monteleone G. Involvement of interleukin-21 in the regulation of colitis associated colon cancer. JEM vol. 208 no. 11 2279-2290.

Monteleone I, Rizzo A, Sarra M, Sica G, Sileri P, Biancone L, MacDonald TT, Pallone F, Monteleone G. Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract. Gastroenterology 2011;141:237–248.

Vendrame F, Dotta F. Comment on: Meagher et al. Neutralization of interleukin-16 protects nonobese diabetic mice from autoimmune type 1 diabetes by a CCL4-dependent mechanism. Diabetes 2010;59:2862-2871. Diabetes (2011); 60(2): e12.

Grieco FA, Vendrame F, Spagnuolo I, Dotta F. Innate immunity and the pathogenesis of type 1 diabetes. Semin Immunopathol. (2011); 33(1): 57-66.

Sarra M, Caruso R, Cupi ML, Monteleone I, Stolfi C, Campione E, Diluvio L, Mazzotta A, Botti E, Chimenti S, Costanzo A, MacDonald TT, Pallone F, Monteleone G. IL-21 Promotes Skin Recruitment of CD4+ Cells and Drives IFN-g–Dependent Epidermal Hyperplasia. J Immunol. 2011 May 1;186(9):5435-42.

Stolfi C, Franzè E, Monteleone I, Caruso R, Franceschilli L, Sileri P, Sica GS, Gaspari AL, Del Vecchio Blanco G, Pallone F, Monteleone G. 2-Methoxy-5-Amino-N-Hydroxybenzamide Sensitizes Colon Cancer Cells to TRAIL-Induced Apoptosis by Regulating Death Receptor 5 and Survivin Expression. Mol Cancer Ther 2011;10:1969-1981.

Biancone L, Petruzziello C, Orlando A, Kohn A, Ardizzone S, Daperno M, Angelucci E, Castiglione F, D’Incà R, Zorzi F, Papi C, Meucci G, Riegler G, Sica G, Rizzello F, Mocciaro F, Onali S, Calabrese E, Cottone M, Pallone F. Cancer in Crohn’s Disease Patients Treated with Infliximab: A Long-term Multicenter Matched Pair Study. Inflamm Bowel Dis. 2011 Mar;17(3):758-66.

Falorni A, Chen S, Zanchetta R, Yu L, Tiberti C, Bacosi ML, Furmaniak J, Bini V, Dotta F, Eisenbarth GS, Smith BR, Betterle C. Measuring adrenal autoantibody response: interlaboratory concordance in the first international serum exchange for the determination of 21-hydroxylase autoantibodies. Clin Immunol (2011); 140(3): 291-299.

Bruno G, De Micheli A, Frontoni S, Monge L, Bonomo M, De Cosmo S, Grassi G, Nicolucci A, Aiello A, Bertuzzi F, Bonora E, Cimino A, Cordera R, de Bigontina G, Di Bartolo P, Dotta F, Frittitta L, Giaccari A, Giorgino F, Gruden G, Marchetti P, Meschi F, Pellegrini MA, Rivellese A, Sesti G. Highlights from “Italian Standards of care for Diabetes Mellitus 2009-2010”. Nutr Metab Cardiovasc Dis. (2011); 21(4): 302-314.

Sarra M, Franze` E, Pallone F, Monteleone G. Targeting interleukin-21 in inflammatory diseases. Expert Opin Ther Targets. 2011 Jun;15(6):695-702.

Bulotta S, Corradino R, Celano M, D’Agostino M, Maiuolo J, Oliverio M, Procopio A,  Iannone M, Rotiroti D, Russo D. Antiproliferative and antioxidant effects on breast cancer cells of oleuropein and its semisynthetic peracetylated derivatives. Food Chem (2011). 127(4):1609-1614.

Durante C, Tallini G, Puxeddu E, Sponziello M, Moretti S, Ligorio C, Cavaliere A, Rhoden KJ, Verrienti A, Maranghi M, Giacomelli L, Russo D, Filetti S. BRAF (V600E) mutation and expression of proangiogenic molecular markers in papillary thyroid carcinomas. European Journal of Endocrinology (2011) 165 455–463.

Sebastiani G, Grieco FA, Spagnuolo I, Galleri L, Cataldo D, Dotta F. Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity. Diabetes Metab Res Rev. (2011); 27(8): 862-866.

Grieco FA, Moretti M, Sebastiani G, Galleri L, Spagnuolo I, Scafetta G, Gulino A, De Smaele E, Maroder M, Dotta F. Delta-cell specific expression of hedgehog pathway Ptch1 receptor in murine and human endocrine pancreas. Diabetes Metab Res Rev. (2011); 27(8): 755-760.

Tiberti C, Yu L, Lucantoni F, Panimolle F, Spagnuolo I, Lenzi A, Eisenbarth GS, Dotta F. Detection of four diabetes specific autoantibodies in a single radioimmunoassay: an innovative high-throughput approach for autoimmune diabetes screening. Clin Exp. Immunol. (2011); 166(3): 317-324.

Stolfi C, Caruso R, Franzè E, Sarra M, De Nitto D, Rizzo A, Pallone F, Monteleone G. Interleukin-25 fails to activate STAT6 and induce alternatively activated macrophages. Immunology. 2011 Jan;132(1):66-77.

Biancone L, Zuzzi S, Ranieri M, Petruzziello C, Calabrese E, Onali S, Ascolani M, Zorzi F, Condino G, Iacobelli S, Pallone F. Fistulizing pattern in Crohn’s disease and pancolitis in ulcerative colitis are independent risk factors for cancer: A single-center cohort study. J Crohns Colitis. 2012 Jun;6(5):578-87.

Petruzziello C, Calabrese E, Onali S, Zuzzi S, Condino G, Ascolani M, Zorzi F, Pallone F, Biancone L. Small bowel capsule endoscopy vs conventional techniques in patients with symptoms highly compatible with Crohn’s Disease. J Crohns Colitis. 2011 Apr;5(2):139-47.

Sponziello ML, Bruno R, Durante C, D’Agostino M, Corradino R, Giannasio P, Ciociola E, Ferretti E, Maranghi M, Verrienti A, De Toma G, Filetti S, Russo D. Growth Factor Receptors Gene Expression and AktPhosphorylation in Benign Human Thyroid Nodules are Unaff ected by Chronic Thyrotropin Suppression. Horm Metab Res 2011;43: 22-25.

Priori R, Iannuccelli C, Alessandri C, Modesti M, Antonazzo B, Di Lollo AC, Valesini G, Di Franco M. Fatigue in Sjogren’s syndrome: relationship with fibromyalgia, clinical and biologic features. Clin Exp Rheumatol. 2010 Nov-Dec;28(6 Suppl 63):S82-6.

Di Franco M, Iannuccelli C, Bazzichi L, Atzeni F, Consensi A, Salaffi F, Pietropaolo M, Alessandri C, Basili S, Olivieri M, Bombardieri S, Valesini G, Sarzi-Puttini P. Misdiagnosis in fibromyalgia: a multicentre study. Clin Exp Rheumatol. 2011 Nov-Dec;29(6 Suppl 69):S104-8.

D’Agostino M, Voce P, Celano M, Sponziello M, Moretti S, Maggisano V, Verrienti A, Durante C, Filetti S, Puxeddu E, Russo D. Sunitinib inhibits tumor vascularity and growth but does not affect Akt and ERK phosphorylation in xenograft tumors. Oncol Rep. (2011); 26(5):1075-80.

Mastroianno S, Torlontano M, Scillitani A, D’Aloiso L, Verrienti A, Bonfitto N, De Bonis A, D’Agruma L, Muscarella LA, Guarnieri V, Dicembrino F, Maranghi M, Durante C, Filetti S. Coexistence of multiple endocrine neoplasia type 1 and type 2 in a large Italian family. Endocrine. 2011 Dec;40(3):481-5.

Tancredi M, Marselli L, Lencioni C, Masini M, Bugliani M, Suleiman M, Masiello P, Boggi U, Filipponi F, Dotta F, Marchetti P, Di Cianni G. Histopathology and ex vivo insulin secretion of pancreatic islets in gestational diabetes: A case report. Islets (2011); 3(5): 231-233.

Sebastiani G, Vendrame F, Dotta F. MicroRNAs as new tools for exploring type 1 diabetes: relevance for immunomodulation and transplantation therapy. Transplantation Proc. (2011); 43(1): 330-332.

Cosco D, Paolino D, Maiuolo J, Russo D, Fresta M. Liposomes as multicompartmental carriers for multidrug delivery in anticancer chemotherapy. Drug Deliv. and Transl. Res. (2011) 1:66–75.

2010

Igoillo-Esteve M, Marselli L, Cunha DA, Ladrière L, Ortis F, Grieco FA, Dotta F, Weir GC, Marchetti P, Eizirik DL, Cnop M. Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes. Diabetologia (2010); 53(7): 1395-1405.

Paolino D, Cosco D, Racanicchi L, Trapasso E, Celia C, Iannone M, Puxeddu E, Costante G, Filetti S, Russo D, Fresta M.Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR: biodistribution, pharmacokinetic features and in vivo antitumor activity. J Control Release. 2010 Jun 1;144(2):144-50.

Durante C, Attard M, Torlontano M, Ronga G, Monzani F, Costante G, Ferdeghini M, Tumino S, Meringolo D, Bruno R, De Toma G, Crocetti U, Montesano T, Dardano A, Lamartina L, Maniglia A, Giacomelli L, Filetti S; Papillary Thyroid Cancer Study Group. Identification and optimal postsurgical follow-up of patients with very low-risk papillary thyroid microcarcinomas.  J Clin Endocrinol Metab. 2010 Nov;95(11):4882-8.

Merlotti D, Gennari L, Dotta F, Lauro D, Nuti R. Mechanisms of impaired bone strenght in type 1 and 2 diabetes. Nutr Metab Cardiovasc Dis. (2010); 20(9): 683-690.

Brozzetti A, Marzotti S, Tortoioli C, Bini V, Giordano R, Dotta F, Betterle C, De Bellis A, Arnaldi G, Toscano V, Arvat E, Bellastella A, Mantero F, Falorni A; Italian Addison Network. Cytotoxic T lymphocyte antigen-4 Ala17 polymorphism is a genetic marker of autoimmune adrenal insufficiency: Italian association study and meta-analysis of European studies. Eur J Endocrinol. (2010); 162(2): 361-369.

Gallwitz B, Haupt A, Kraus P, Peters N, Petto H, Dotta F, Petto H, Poll L, Rose L, Schernthaner G. Changes in body composition after 9 months of treatment with exenatide twice daily versus glimepiride: comment letter on Jendle et al. Diabetes Obes Metab. (2010); 12(12): 1127-1128.

Roep BO, Kleijwegt FS, van Halteren AG, Bonato V, Boggi U, Vendrame F, Marchetti P, Dotta F. Islet inflammation and CXCL10 in recent-onset type 1 diabetes. Clin Exp Immunol. (2010); 159(3): 338-343.

Olivieri A, De Angelis S, Dionisi S, D’Annunzio G, Locatelli M, Marinaro M, Bonato V, Amendola A, Songini M, Velluzzi F, Schirru C, Cotichini R, Stazi MA, Dotta F, Lorini R, Bottazzo GF, Boirivant M. Serum transforming growth factor β1 during diabetes development in non-obese diabetic mice and humans. Clin Exp Immunol. (2010); 162(3): 407-414.

Castellone MD, Verrienti A, Magendra Rao D, Sponziello M, Fabbro D, Muthu M, Durante C, Maranghi M, Damante G, Pizzolitto S, Costante G, Russo D, Santoro M, Filetti S. A novel de novo germ-line V292M mutation in the extracellular region of RET in a patient with phaeochromocytoma and medullary thyroid carcinoma: functional characterization. Clin Endocrinol (Oxf). 2010 Oct;73(4):529-34.

Dotta F, Galleri L, Sebastiani G, Vendrame F. Virus infections: lessons from pancreas histology. Curr Diab Rep. (2010); 10(5): 357-361.

Pianta A, Puppin C, Franzoni A, Fabbro D, Di Loreto C, Bulotta S, Deganuto M, Paron I, Tell G, Puxeddu E, Filetti S, Russo D, Damante G.Nucleophosmin is overexpressed in thyroid tumors. Biochem Biophys Res Commun. 2010 Jul 2;397(3):499-504.

2009

Priori R, Alessandri C, Magrini L, Cassarà EA, Ceccarelli F, Modesti M, Croia C, Bombardieri M, Valesini G. Nucleosome accumulation and reduction of C-reactive protein are associated with the generation of anti-nuclear antibodies in patients with rheumatoid arthritis treated with adalimumab, but not with etanercept. Ann Rheum Dis. 2009 Sep;68(9):1514-6.

Costante G, Durante C, Francis Z, Schlumberger M, Filetti S. Determination of calcitonin levels in C-cell disease: clinical interest and potential pitfalls. Nat Clin Pract Endocrinol Metab. 2009 Jan;5(1):35-44.

La Marca A, Marzotti S, Brozzetti A, Stabile G, Artenisio AC, Bini V, Giordano R, De Bellis A, Volpe A, Falorni A; Italian Addison Network. Primary ovarian insufficiency due to steroidogenic cell autoimmunity is associated with a preserved pool of functioning follicles. J Clin Endocrinol Metab. (2009); 94(10): 3816-23.

Valesini G, Alessandri C. Anticitrullinated protein/peptide antibodies and rheumatoid factors: two distinct autoantibody systems. Arthritis Res Ther. 2009;11(5):125.

Tiberti C, Shashaj B, Verrienti A, Vecci EG, Lucantoni F, Masotti D, Morano S, Sulli N, Dotta F. GAD and IA-2 autoantibody detection in type 1 diabetic patient saliva. Clin Immunol. (2009); 131(2): 271-276.

Bosi E, Dotta F, Jia Y, Goodman M. Vildagliptin plus metformin combination therapy provides superior glycaemic control to individual monotherapy in treatment-naive patients with type 2 diabetes mellitus. Diabetes Obes Metab. (2009); 11(5): 506-515.

Bolli G, Dotta F, Colin L, Minic B, Goodman M. Comparison of vildagliptin and pioglitazone in patients with type 2 diabetes inadequately controlled with metformin. Diabetes Obes Metab. (2009); 11(6): 589-595.

Alessandri C, Conti F, Conigliaro P, Mancini R, Massaro L, Valesini G. Seronegative autoimmune diseases. Ann N Y Acad Sci. 2009 Sep;1173:52-9.

Alessandri C, Scrivo R, Spinelli FR, Ceccarelli F, Magrini L, Priori R, Valesini G. Autoantibody production in anti-TNF-alpha-treated patients. Ann N Y Acad Sci. 2007 Sep;1110:319-29. Review.

Dotta F. Innate immunity and human insulitis during beta-cell Coxsackie B4 infection. J Med Virol. (2009); 81: 202.

Bonato V, Cataldo D, Dotta F, Carmellini M. Diagnosis and approach to posttransplant diabetes. Curr Diab Rep. (2009); 9(4): 317-323.

Scrivo R, Conti F, Spinelli FR, Truglia S, Magrini L, Di Franco M, Ceccarelli F, Valesini G. Switching between TNFalpha antagonists in rheumatoid arthritis: personal experience and review of the literature. Reumatismo. 2009 Apr-Jun;61(2):107-17. Review.

2008

Margutti P, Matarrese P, Conti F, Colasanti T, Delunardo F, Capozzi A, Garofalo T, Profumo E, Riganò R, Siracusano A, Alessandri C, Salvati B, Valesini G, Malorni W, Sorice M, Ortona E. Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis. Blood. 2008 May 1;111(9):4559-70.

Tiberti C, Giordano C, Locatelli M, Bosi E, Bottazzo GF, Buzzetti R, Cucinotta D, Galluzzo A, Falorni A, Dotta F. Identification of tyrosine posphatase 2 (256-760) construct as a new, sensitive marker for the detection of islet autoimmunity in type 2 diabetic patients: the non-insulin requiring autoimmune diabetes (NIRAD) study 2. Diabetes (2008); 57(5): 1276-1283.

Puxeddu E, Durante C, Avenia N, Filetti S, Russo D. Clinical implications of BRAF mutation in thyroid carcinoma. Trends Endocrinol Metab. 2008 May-Jun;19(4):138-45.

Egan CG, Lavery R, Caporali F, Fondelli C, Laghi-Pasini F, Dotta F, Sorrentino V. Generalised reduction of putative endothelial progenitors and CXCR4-positive peripheral blood cells in type 2 diabetes. Diabetologia (2008); 51(7): 1296-1305.

Torlontano M, Durante C, Torrente I, Crocetti U, Augello G, Ronga G, Montesano T, Travascio L, Verrienti A, Bruno R, Santini S, D’Arcangelo P, Dallapiccola B, Filetti S, Trischitta V. Type 2 deiodinase polymorphism (threonine 92 alanine) predicts L-thyroxine dose to achieve target thyrotropin levels in thyroidectomized patients. J Clin Endocrinol Metab. 2008 Mar;93(3):910-3.

Ferretti E, Tosi E, Po A, Scipioni A, Morisi R, Espinola MS, Russo D, Durante C, Schlumberger M, Screpanti I, Filetti S, Gulino A. Notch signaling is involved in expression of thyrocyte differentiation markers and is down-regulated in thyroid tumors. J Clin Endocrinol Metab. 2008 Oct;93(10):4080-7.

Dotta F, Fondelli C, Falorni A. Can NK cells be a therapeutic target in human type 1 diabetes? Eur J Immunol. (2008); 38(11): 2961-2963.

Crocetti U, Durante C, Attard M, Maniglia A, Tumino S, Bruno R, Bonfitto N, Dicembrino F, Varraso A, Meringolo D, Filetti S, Trischitta V, Torlontano M. Predictive value of recombinant human TSH stimulation and neck ultrasonography in differentiated thyroid cancer patients. Thyroid. 2008 Oct;18(10):1049-53.

Stolfi C, Fina D, Caruso R, Caprioli F, Sarra M, Fantini MC, Rizzo A, Pallone F, Monteleone G. Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid. Biochem Pharmacol. 2008 Feb 1;75(3): 668-676.

Celano M, Schenone S, Cosco D, Navarra M, Puxeddu E, Racanicchi L, Brullo C, Varano E, Alcaro S, Ferretti E, Botta G, Filetti S, Fresta M, Botta M, Russo D. Cytotoxic effects of a novel pyrazolopyrimidine derivative entrapped in liposomes in anaplastic thyroid cancer cells in vitro and in xenograft tumors in vivo. Endocr Relat Cancer. 2008 Jun;15(2):499-510.

Alessandri C, Priori R, Modesti M, Mancini R, Valesini G. The role of anti-cyclic cytrullinate antibodies testing in rheumatoid  arthritis. Clin Rev Allergy Immunol. 2008 Feb;34(1):45-9.

Puppin C, Fabbro D, Dima M, Di Loreto C, Puxeddu E, Filetti S, Russo D, Damante G. High periostin expression correlates with aggressiveness in papillary thyroid carcinomas. J Endocrinol. 2008 May;197(2):401-8.

Bolli G, Dotta F, Rochotte E, Cohen SE. Efficacy and tolerability of vildagliptin vs. pioglitazone when added to metformin: a 24-week, randomized, double-blind study. Diabetes Obes Metab. (2008); 10(1): 82-90.

Gallo R, Grieco FA, Marselli L, Ferretti E, Gulino A, Marchetti P, Dotta F. Hedgehog signaling during expansion of human pancreatic islet-derived precursors. Ann NY Acad Sci. (2008); 1150: 43-45.

Bruno G, De Micheli G, Fedele D, Monge L, Bonomo M, Consoli A, De Cosmo S, Di Bartolo P, Di Benedetto A, Di Cianni G, Dotta F, Giaccari A, Giorgino F, Grassi G, Gruden G, Mannino D, Orlandini D, Ponziani MC, Vaccaro O, Vitacolonna E. Italian standards for diabetes mellitus 2007: executive summary. Acta Diabetol. (2008); 45: 107-127.

Vendrame F, Verrienti A, Parlapiano C, Filetti S, Dotta F, Morano S. Thyrotoxic periodic paralysis in an Italian man: clinical manifestation and genetic analysis. Ann Clin Biochem. (2008); 45(Pt 2): 218-220.

Marchetti P, Dotta F, Lauro D, Purrello F. An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment. Regul Pept. (2008); 146(1-3): 4-11.

Bonato V, Barni R, Cataldo D, Collini A, Ruggieri G, De Bartolomeis C, Dotta F, Carmellini M. Analysis of posttransplant diabetes mellitus prevalence in a population of kidney transplant recipients. Transplant Proc. (2008); 40(6): 1888-1890.

Durante C, Cava F, Paciaroni A, Filetti S. Benign thyroid nodules: diagnostic and therapeutic approach. Recenti Prog Med. 2008 May;99(5):263-70.

2007

Caruso R, Fina D, Peluso I, Stolfi C, Fantini MC, Gioia V, Caprioli F, Del Vecchio Blanco G, Paoluzi OA, Macdonald TT, Pallone F, Monteleone G. A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells. Gastroenterology. 2007 Jan;132(1):166-75.

Fina D, Sarra M, Caruso R, Del Vecchio Blanco G, Pallone F, Macdonald TT, Monteleone G. Interleukin-21 Contributes To The Mucosal T Helper Cell Type 1 Response In Celiac Disease. Gut. 2007 Oct 26.

Margutti P, Matarrese P, Conti F, Colasanti T, Delunardo F, Capozzi A, Garofalo T, Profumo E, Rigano R, Siracusano A, Alessandri C, Salvati B, Valesini G, Malorni W, Sorice M, Ortona E Blood. Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis. Blood 2007 Nov 9.

Dotta F, Censini S, van Halteren AG, Marselli L, Masini M, Dionisi S, Mosca F, Boggi U, Onetti Muda A, Del Prato S, Elliott JF, Covacci A, Rappuoli R, Roep BO, Marchetti P. Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci USA (2007); 104(12): 5115-5120.

Gallo R, Gambelli F, Gava B, Sasdelli F, Tellone V, Masini M, Marchetti P, Dotta F, Sorrentino V. Generation and expansion of multipotent mesenchymal progenitor cells from cultured human pancreatic islets. Cell Death Differ. (2007); 14(11): 1860-1871.

Buzzetti R, Di Pietro S, Giaccari A, Petrone A, Locatelli M, Suraci C, Capizzi M, Arpi ML Bazzigaluppi E, Dotta F, Bosi E. High titer of autoantibodies to GAD identifies a specific phenotype of adult-onset autoimmune diabetes. Diabetes Care (2007); 30(4): 932-938.

Sorice M, Longo A, Capozzi A, Garofalo T, Misasi R, Alessandri C, Conti F, Buttari B, Riganò R, Ortona E, Valesini G. Anti -beta2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts. Arthritis Rheum. 2007 Aug;56(8):2687-97.

Costante G, Meringolo D, Durante C, Bianchi D, Nocera M, Tumino S, Crocetti U, Attard M, Maranghi M, Torlontano M, Filetti S. Predictive value of serum calcitonin levels for preoperative diagnosis of medullary thyroid carcinoma in a cohort of 5817 consecutive patients with thyroid nodules. J Clin Endocrinol Metab. 2007 Feb;92(2):450-5.

Durante C, Puxeddu E, Ferretti E, Morisi R, Moretti S, Bruno R, Barbi F, Avenia N, Scipioni A, Verrienti A, Tosi E, Cavaliere A, Gulino A, Filetti S, Russo D. BRAF mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism. J Clin Endocrinol Metab. 2007 Jul; 92 (7): 2840-3.

Peluso I, Fantini MC, Fina D, Caruso R, Boirivant M, MacDonald TT, Pallone F, Monteleone G. IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes. J Immunol. 2007 Jan 15;178(2):732-9.

Caruso R, Fina D, Peluso I, Fantini MC, Tosti C, Del Vecchio Blanco G, Paoluzi OA, Caprioli F, Andrei F, Stolfi C, Romano M, Ricci V, MacDonald TT, Pallone F, Monteleone G. IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis. J Immunol. 2007 May 1;178(9):5957-65.

Fantini MC, Rizzo A, Fina D, Caruso R, Becker C, Neurath MF, Macdonald TT, Pallone F, Monteleone G. IL-21 regulates experimental colitis by modulating the balance between Treg and Th17 cells. Eur J Immunol. 2007 Nov;37(11):3155-63.

Faggiano A, Caillou B, Lacroix L, Talbot M, Filetti S, Bidart JM, Schlumberger M. Functional Characterization of Human Thyroid Tissue with Immunohistochemistry. Thyroid 2007 Mar;17(3):203-211. 

Ronga G, Bruno R, Puxeddu E, Calcinaro F, Montesano T, Travascio L, Colandrea M, Durante C, Maranghi M, Filetti S, Russo D. Radioiodine uptake in non-lactating mammary glands: evidence for a causative role of hyperprolactinemia. Thyroid. 2007 Apr;17(4):363-6. 

Scipioni A, Ferretti E, Soda G, Tosi E, Bruno R, Costante G, Meringolo D, Arturi F, Durante C, Amorosi A, Foschini MP, Nardi F, Russo D, Filetti S BRAF mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism. Thyroid. 2007 Aug; 17(7): 613-8.

Stolfi C, Fina D, Caruso R, Caprioli F, Sarra M, Fantini MC, Rizzo A, Pallone F, Monteleone G. Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer  cells by 5-aminosalicylic acid. Biochem Pharmacol. 2007 Sep 29.

Peluso I, Fina D, Caruso R, Stolfi C, Caprioli F, Fantini MC, Caspani G, Grossi E, Di Iorio L, Paone FM, Pallone F, Monteleone G. Lactobacillus paracasei subsp. paracasei B21060 suppresses human T-cell proliferation. Infect Immun. 2007 Apr;75(4):1730-7.

Giannakakis K, Massella L, Grassetti D, Dotta F, Perez M, Onetti-Muda A. Type VII collagen in Alport syndrome. Nephrol Dial Transplant. (2007); 22(12): 3501-3507.

Alessandri C, Scrivo R, Spinelli FR, Ceccarelli F, Magrini L, Priori R, Valesini G. Autoantibody production in anti-TNF-alpha-treated patients. Ann N Y Acad Sci. 2007 Sep;1110:319-29. Review.

Morisi R, Celano M, Tosi E, Schenone S, Navarra M, Ferretti E, Costante G, Durante C, Botta G, D’Agostino M, Brullo C, Filetti S, Botta M, Russo D. Growth inhibition of medullary thyroid carcinoma cells by pyrazolo-pyrimidine derivates. J Endocrinol Invest. 2007 Nov;30(10):RC31-RC34.

2005

Monteleone G, Monteleone I, Fina D, Vavassori P, Del Vecchio Blanco G, Caruso R, Tersigni R, Alessandroni L, Biancone L, Naccari G, Macdonald T, and Pallone F. Interleukin-21 Enhances T-Helper Cell Type I Signaling and Interferon- Production in Crohn’s Disease. Gastroenterology 2005; 128: 687 – 694.

Putnam AL, Vendrame F, Dotta F, Gottlieb PA. CD4+CD25 high regulatory T cells in human autoimmune diabetes. J Autoimmun. (2005); 24(1): 55-62.

Calcinaro F, Dionisi S, Marinaro M, Candeloro P, Bonato V, Marzotti S, Corneli RB, Ferretti E, Gulino A, Grasso F, De Simone C, Di Mario U, Falorni A, Boirivant, Dotta F. Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse. Diabetologia (2005); 48(8): 1565-1575.

Fourlanos S, Dotta F, Greenbaum CJ, Palmer JP, Rolandsson O, Colman PG, Harrison LC. Latent Autoimmune Diabetes in Adults (LADA) should be less latent. Diabetologia (2005); 48(11): 2206-2212.

Tiberti C, Verrienti A, Fiore B, Yu L, Eisenbarth GS, Dotta F, Di Mario U. IA-2 combined epitope assay: a new, highly sensitive approach to evaluate IA-2 humoral autoimmunity in type 1 diabetes. Clin Immunol. (2005); 115(3): 260-267.

Dotta F, Fondelli C, Vendrame F, Gianani R. Pathological changes in human islets. Curr Opin. Endocr & Diabetes (2005); 12: 285-290.

Anastasi E, Santangelo C, Bulotta A, Dotta F, Argenti B, Mincione C, Gulino A, Maroder M, Perfetti R, Di Mario U. The acquisition of an insulin-secreting phenotype by HGF-treated rat pancreatic ductal cells (ARIP) is associated with the development of susceptibility to cytokine-induced apoptosis. J Mol Endocrinol. (2005); 34(2): 367-376.

Vendrame F, Santangelo C, Misasi R, Dionisi S, Gizzi C, Realacci M, Grassetti D, Di Mario U, Dotta F. Defective lymphocyte caspase-3 expression in type 1 diabetes mellitus. Eur J Endocrinol. (2005); 152(1): 119-125.

Santangelo C, Scipioni A, Marselli L, Marchetti P, Dotta F. Suppressor of cytokine signaling gene expression in human pancreatic islets: modulation by cytokines. Eur J Endocrinol.(2005); 152(3): 485-489.

Roep B, Van Halteren A, Boggi U, Marchetti P, Dotta F. Islet autoreactivity in pancreas draining lymph nodes in recent onset tye 1 diabetes. Endocr J. (2005); 52: 162-164.

Wilkinson A, Davidson J, Dotta F, Home P, Keown P, Kiberd B, Jardine A, Levitt N, Marchetti P, Markell M, Naicker S, O’Connell P, Schnitzler M, Standl E, Torregrosa JV, Uchida K, Valentine F, Villamil F, Vincenti F, Wissing M. Guidelines for the treatment and management of new-onset diabetes after transplantation. Clin Transplant. (2005); 19(3): 291-298.

Dotta F, Fondelli C, Di Mario U. Type 1 diabetes mellitus as a polygenic multifactorial disease: immunopathogenic mechanisms of beta-cell destruction. Acta Biomed. (2005); 76 Suppl 3: 14-18.

2003

Biancone L, Fiori R, Tosti C, Marinetti A, Catarinacci M, De Nigris F, Simonetti G, Pallone F. Virtual colonoscopy compared with conventional colonoscopy for structuring postoperative recurrence in Crohn’s disease. Inflamm Bowel Dis. 2003 Nov;9(6):343-50.

Tiberti C, Bao F, Bonamico M, Verrienti A, Picarelli A, Di Tola M, Ferri M, Vecci E, Dotta F, Eisenbarth GS, Di Mario U. Celiac disease-associated transglutaminase autoantibody target domains at diagnosis are age and sex dependent. Clin Immunol. (2003); 109(3): 318-324.

Davidson J, Wilkinson A, Dantal J, Dotta F, Haller H, Hernandez D, Kasiske BL, Kiberd B, Krentz A, Legendre C, Marchetti P, Markell M, van der Woude FJ, Wheeler DC; International Expert Panel. New-onset diabetes after transplantation: 2003 International consensus guidelines. Proceedings of an International expert panel meeting. Barcelona, Spain, 19 february 2003. Transplantation (2003); 75(10): 3-24.

Biancone L, Tosti C, Fina D, Fantini M, De Nigris F, Geremia A, Pallone F. Maintenance treatment of Crohn’s disease. Aliment Pharmacol Ther. 2003 Jun;17 Suppl 2:31-7.

Biancone L, Fantini M, Tosti C, Bozzi R, Vavassori P, Pallone F. Fecal alpha 1-antitrypsin clearance as a marker of clinical relapse in patients with Crohn’s disease of the distal ileum. Eur J Gastroenterol Hepatol. 2003 Mar;15(3):261-6.

2002

Lupi R, Dotta F, Marselli L, Del Guerra S, Masini M, Santangelo C, Patané G, Boggi U, Piro S, Anello M, Bergamini E, Mosca F, Di Mario U, Del Prato S, Marchetti P. Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated. Diabetes (2002); 51(5): 1437-1442.

Miao D, Yu L, Tiberti C, Cuthbertson DD, Rewers M, Di Mario U, Eisenbarth GS, Dotta F. ICA512 (IA-2) epitope specific assays distinguish transient from diabetes associated autoantibodies. J Autoimmun. (2002); 18(2): 191-196.

Farilla L, Tiberti C, Luzzago A, Yu L, Eisenbarth GS, Cortese R, Dotta F, Di Mario U. Application of phage display peptide library to autoimmune diabetes: identification of IA-2/ICA512bdc dominant autoantigenic epitopes. Eur J Immunol. (2002); 32(5): 1420-1427.

Biancone L, Geboes K, Spagnoli LG, Del Vecchio Blanco G, Monteleone G, Vavassori P, Palmieri G, Chimenti S, Pallone F. Metastatic Crohn’s disease of the forehead. Inflamm Bowel Dis. 2002 Mar;8(2):101-5.

Biancone L, De Nigris F, Del Vecchio Blanco G, Monteleone I, Valvassori P, Geremia A, Pallone F. Monitoring the activity of Crohn’s disease. Aliment Pharmacol Ther. 2002 Jul;16 Suppl 4:29-33.

Dotta F, Vendrame F. Neonatal syndromes of polyendocrinopathy. Endocrinol Metab Clin North Am. (2002); 31(2): 283-293.

Biancone L, Monteleone I, Del Vecchio Blanco G, Vavassori P, Pallone F. Resident bacterial flora and immune system. Dig Liver Dis. 2002 Sep;34 Suppl 2:S37-43.

Trincavelli ML, Marselli L, Falleni A, Gremigni V, Ragge E, Dotta F, Santangelo C, Marchetti P, Lucacchini A, Martini C. Upregulation of mitochondrial peripheral benzodiazepine receptor expression by cytokine-induced damage of human pancreatic islets. J Cell Biochem. (2002); 84(3): 636-644.

Dotta F, Anastasi E. Nuove fonti di cellule producenti insulina. Il Diabete (2002); 14: 128-133.